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231113 Society for Neuroscience - Washington DC Day 3 - P1041946-Enhanced-NR_edit (1) (1).

Advancing
Neuro-Muscular
Health

Neuro-Muscular Labs, where the hyphen is intentional. Our research bridges the nervous and muscular systems, advancing discoveries from molecular mechanisms to clinical therapies. Explore how our labs push the boundaries of science to improve human health

Neuro-Muscular Labs, a multi-lab neuroscience collective, is dedicated to unraveling the complexities of the nervous and muscular systems through a deeply collaborative and integrative approach. By uniting expertise in molecular biology, cellular neuroscience, and systems-level investigations, our researchers work together to understand how fundamental processes break down in neuromuscular and neurological diseases. 

Across our labs, there is a strong focus on uncovering the mechanisms of axon degeneration, myelin instability, and age-related changes that drive disease onset and progression. This shared commitment to bridging basic science with translational research enables us to identify novel therapeutic targets and inform the development of innovative interventions.

Our teams are driven by a mission to translate discoveries from bench to bedside, ultimately improving outcomes for patients facing debilitating neuromuscular and neurological conditions. Through cutting-edge techniques, ranging from advanced imaging and genetic manipulation to preclinical modeling and clinical trial integration, we generate insights that not only advance fundamental scientific understanding but also have immediate relevance for therapy development.

Our emphasis on collaboration not only accelerates scientific discovery but also strengthens the training and mentorship of the next generation of neuroscientists. At Neuro-Muscular Labs, we believe that working seamlessly across disciplines and scales is essential to solving the intricate puzzle of neuromuscular diseases and delivering tangible impact for the individuals and families we aim to serve.

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Advanced Imaging

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Electrophysiology and Functional Analysis

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Disease Model Across Scales

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Computational Circuit Modeling

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W. David Arnold, MD

Professor and NextGen Executive Director

Translational Neuromuscular Physiology

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Smita Saxena, PhD

Professor

Neuronal and Circuit Vulnerability in Disease

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Hiroshi Nishimune, PhD

Professor

NMJ Development and Degeneration

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Ryan Castoro, DO

Assistant Professor

Proprioception and Peripheral Nerve Aging

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Bornali Kundu, MD, PhD

Assistant Professor

Memory Networks and Brain Stimulation

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Kathryn Moss, PhD

Assistant Professor

Dysmyelinating Neuropathy Mechanisms

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Curtis Nutter, PhD

Assistant Professor

RNA Repeat Expansion Neurological Disease

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Andrea Sierra Delgado, MD

Assistant Professor

Gene Therapy for Rare Neurological Disease

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Kristina Kelly, DPT

Assistant Professor

Weakness and Fatigue in Aging and Disease

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New Publication

Dec 17, 2025

Dr. Moss and Marvis Arowolo published a research article in Glia titled "Aberrant Molecular Myelin Architecture in Charcot-Marie-Tooth Disease Type 1A and Hereditary Neuropathy with Liability to Pressure Palsies"

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New SfN Regional Chapter

Dec 1, 2025

The new SfN regional chapter "Missouri Show-Me Neuroscience" has been approved.

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SfN MiniSymposium

Nov 16, 2025

Dr. Saxena and Dr. Moss organized a MiniSymposium at the 2025 SfN meeting, which featured a talk by Fereshteh Darvishi (Arnold Lab).

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SfN Poster Presentations

Nov 15, 2025

Fereshteh Darvishi (Arnold Lab), David Fague (Kundu Lab), Vladimir Omelyusik (Kundu Lab) and Marvis Arowolo (Moss Lab) presented posters at the 2025 SfN meeting.

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HSRD Poster Presentations

Nov 14, 2025

Health Sciences Research Day is an annual University of Missouri symposium that showcases original research and educational innovations by students and trainees across the health sciences.

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NML Winter Social 2025

NML members had a potluck dinner at Dr. Arnold's house.

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2025 Society for Neuroscience Meeting

Several NML members attended the 2025 SfN meeting in San Diego, CA.

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NML Summer Picnic 2025

NML members connected at Stephen's Lake Park for a cookout.

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Bio Nexus Event KC

Dave Arnold speaking at the 2023 BioNexus KC Collaborate2Cure Rare Disease event.

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